BIIB - Biogen Inc

[Spekulatius]

https://www.statnews.com/2021/06/10/third-member-of-fda-expert-committee-resigns-over-controversial-alzheimers-therapy-decision/

[no_free_lunch]

Thanks @patience_and_focus, you clearly are more informed than I am on this topic.

 

Is it not true that this is the first drug that slowed the growth of the plaques?  I know others have researched towards delaying plaque build up but has anything else actually worked?  I get that the plaque may just be a symptom but from what I have read it may play a role in disrupting neural communications.

Edited June 11, 2021 by no_free_lunch

[Spekulatius]

7 hours ago, no_free_lunch said:

Thanks @patience_and_focus, you clearly are more informed than I am on this topic.

 

Is it not true that this is the first drug that slowed the growth of the plaques?  I know others have researched towards delaying plaque build up but has anything else actually worked?  I get that the plaque may just be a symptom but from what I have read it may play a role in disrupting neural communications.

The Biogen drug does reduce the amyloid plaques, which was what it’s designed to do, but it does not objectively improve the patient outcome apparently. It seems that the plaques are a symptom but not the true underlying cause of the disease and reducing them does not help the patients.

 

I think the last word isn’t really said about this. There will be some fallout from this decision. I also suspect some wheels have been greased there at the right spots on Biogen’s side.