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What are you buying today?

LowIQinvestor

By LowIQinvestor
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Gregmal Newbie

Gregmal

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Added back a smidge of CRSP. Guessing its down because Biden again vowed to cure cancer....

 

 

Would love to hear your thesis on CRSP?

 

I wrote up the theme a few years ago, I believe it was here. But basically you've got a massive TAM, very long duration runway before anything(positive or negative) will come to fruition, and just continuous positive news flow. CRSP has the best combination of reputable partners and respected scientists on board and is way ahead of the pack in terms of advancing a product(CTX001) to market. Dig around a little in the field(I have a lot of family and friends who work in the space) and you'll repeatedly hear about how CRISPR is basically a once in a generation breakthrough and that the majority of future work being done in a lot of areas utilizes a CRISPR platform. There's non guarantee which company holds the monetization key to all of this, or even if the existing court rulings stand; you've also got an evolving platform as the targeting techniques evolve...but again, your runway is long and there should be quite a bit of money to be made trading these things along the way. I think when I first wrote up as few of these CRSP was around $30 or something. EDIT 20s and NTLA lows teens. Since then you've gotten BEAM and also RPTX come public. Ive got a few shares in nonpublic companies as well. If there was ever a sector/theme where you just want to sprinkle money and then wait for the 10+ bagger, its here IMO.

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Castanza
Castanza

Agreed, enjoyed the writeup. I've been accumulating a position as well. 

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Gregmal Newbie

Gregmal

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It just depends on your risk/speculation tolerance but when I started it I had the basket a hair below 10%. I reduced along the way as I always try to recoup my original investment as fast as possible(at least when I am pretty blatantly speculating) while maintaining a respectable exposure for myself. I cut the basket down to about 2% towards end of 2019 and early 2020. Kicked it back up to about 5% during the Gift of Covid Firesale and have basically just been trading around a core since. The thing I'd focus on is really just staying up to date with the people involved and the progress being made to market as well as the institutional partners. CRSP is a clear leader. But the science/application end is evolving so something like RPTX could be interesting. If you are a normal dude and not filthy rich I think I'd probably just say chuck $5-$10k per name at a select few and let it ride while peeling off your original capital hoping to eventually trade your way into some free shares or maybe check out some ARKG although with that its got the exposure but I hate their concentration and conviction in NVTA, despite having made a lot of money both long and short in that name, I think fundamentally it's a Ponzi scheme and its one of ARKs largest holdings.

 

EDIT: I'd clarify on the allocation amount, depending on where you are in your earnings life cycle, maybe take a couple months worth of salary as your benchmark. Its different for everyone so 2% of portfolio if you're 60 is different than if you're 40 or 20. So is 5-10K per name. So I'd say the lesser of 2% as a basket or a few months of salary...although just be warned I hate giving uniform investment advice and its really just individual preference to which my preference can and sometimes are very different than that of others....

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wescobrk Newbie

wescobrk

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It is very rare that I short things but I have a small short on the nasdaq. I will cover it most likely within a week or so as I don't usually like to short but this seems like a good day to put it on. Of course, we could rally tomorrow so that is why it is a small position.

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Gregmal Newbie

Gregmal

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After a little debating also took Trump to win NH at +275. Anecdotally Ive found NH be unique and the folks there less stupid and liberal than those in MA and CT. Matched it on a payout basis to more or less wash my Biden -170 bet. If Joe wins I win money and if Trump wins NH(regardless) I come out slightly ahead as well. Hedge trade!

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rkbabang Newbie

rkbabang

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After a little debating also took Trump to win NH at +275. Anecdotally Ive found NH be unique and the folks there less stupid and liberal than those in MA and CT. Matched it on a payout basis to more or less wash my Biden -170 bet. If Joe wins I win money and if Trump wins NH(regardless) I come out slightly ahead as well. Hedge trade!

 

NH has been swamped with people moving from liberal states like MA.  I've watched the town I live in turn from solidly red 10 years ago to purple to blue.  It's frustrating to say the least.  They flee the states they've destroyed only to destroy their new states in the same way.  They are like a plague of locusts constantly destroying then looking for a new fertile field.  Ex-CA residents are in the process of doing this to TX as we speak.

 

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Gregmal Newbie

Gregmal

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Hey, only in America can you shit in your bed and then just pickup and sleep in someone else's. Overall though, I think the underlying messages of this election were very positive. One, you have indisputably destroyed anything that was left(to me, not much, but I'm not gullible) of the media and pollsters credibility. Two, you saw very clear messages in places like Kenosha; a blatant reverse course from 2016 directly tied to the anarchy and chaos position of the left. Three, Hispanics, particularly in Florida and Texas, roundly rejecting Democrats as the party of socialism. While matching Trump's voter enthusiasm with another candidate will be hard for the GOP, you'd think they pretty handily take much more of the popular vote and votes in swing states with a less divisive candidate. And at the same time, the Democrats should proceed with caution and who knows, maybe realize some of the ways of their errors with regard to policies and if they come back to the middle, its all good for everyone anyway.

 

Best line I saw last night was on Twitter. Some stupid liberal chick was spewing nonsense about "it's not a red state blue state issue at this point, its a white issue"...to which someone methodically blew her peanut sized brain out of its shell by tweeting exit polls showing that Trump actually improved DRASTICALLY amongst ALL demographics...except white males!

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winjitsu Newbie

winjitsu

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Gregmal where did you bet on? Could not find a platform, though this could be based on state. In the late part of the night, I was seeing odds of 3-1 Trump on Betfair which was insane considering the commentary on the news on the mail in ballots. They've since reversed course, but clearly a missed trade opportunity

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Gregmal Newbie

Gregmal

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Gregmal where did you bet on? Could not find a platform, though this could be based on state. In the late part of the night, I was seeing odds of 3-1 Trump on Betfair which was insane considering the commentary on the news on the mail in ballots. They've since reversed course, but clearly a missed trade opportunity

 

mybookie.ag

 

A few caveats...1) daily wire limit is only $2,500. 2) Its an offshore based operation so you effectively have no recourse should they try to screw you. The limits on $ in a way for me are to remind myself that obviously its still gambling(not best use of money) and also to only screw around with insignificant sums in the event there is an issue with #2. I've looked at some of the legal operations that have sprouted up in past few years but dont think they make a huge difference. I tried FanDuel but kept running into issues where they couldn't verify locations and wouldn't allow bets. I also dont gamble a lot. Maybe a half dozen events in the last 10-15 years.

 

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rkbabang Newbie

rkbabang

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Gregmal where did you bet on? Could not find a platform, though this could be based on state. In the late part of the night, I was seeing odds of 3-1 Trump on Betfair which was insane considering the commentary on the news on the mail in ballots. They've since reversed course, but clearly a missed trade opportunity

 

mybookie.ag

 

A few caveats...1) daily wire limit is only $2,500. 2) Its an offshore based operation so you effectively have no recourse should they try to screw you. The limits on $ in a way for me are to remind myself that obviously its still gambling(not best use of money) and also to only screw around with insignificant sums in the event there is an issue with #2. I've looked at some of the legal operations that have sprouted up in past few years but dont think they make a huge difference. I tried FanDuel but kept running into issues where they couldn't verify locations and wouldn't allow bets. I also dont gamble a lot. Maybe a half dozen events in the last 10-15 years.

 

 

The name "mybookie" is also another reminder that it is gambling I think.  Sounds like fun with small amounts though.

 

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kab60 Newbie

kab60

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Bought some Teva yesterday, results out today. Really cheap on a P/FCF basis, lots of noise around litigation. Should be in a place to return money to shareholders in 3 years time. Expanding margins, growth plus litigation settlement could see this triple in 3 years but there are obviously risks here.

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